Thérèse was often sick; she began to suffer from nervous tremors. The tremors started one night after her uncle took her for a walk and began to talk about Zélie. Assuming that she was cold, the family covered Therese with blankets, but the tremors continued; she clenched her teeth and could not speak. The family called Dr. Notta, who could make no diagnosis.[16] In 1882, Dr Gayral diagnosed that Thérèse "reacts to an emotional frustration with a neurotic attack."[17] An alarmed, but cloistered, Pauline began to write letters to Thérèse and attempted various strategies to intervene. Eventually Thérèse recovered after she had turned to gaze at a statue of the Blessed Virgin Mary and reported on 13 May 1883 that she had seen the Virgin smile at her.[18][19] She wrote: "Our Blessed Lady has come to me, she has smiled upon me. How happy I am".[20] The date 13 May later became a significant Marian date at Our Lady of Fátima, long after Thérèse's death.
http://en.wikipedia.org/wiki/Thérèse_of_Lisieux
http://en.wikipedia.org/wiki/Thérèse_of_Lisieux